Prior to WL, an ambulatory run-in period was imposed for each subject to insure stabilization of body weight (± 2 kg during 4 weeks). During the body weight stabilization, a three-day food dietary record was used to determine an individual’s daily food and beverage consumption to estimate their total daily caloric intake (2 weekdays and 1 weekend day). The subjects were randomly divided (according to age, gender and BMI) into two groups (rapid WL and slow WL). Rapid WL and slow WL, based on the lost weight (at least 5 %), were defined over a period of 5 weeks and 15 weeks, respectively (18). The prescribed calorie-restricted diet contained 15% protein, 30% to 35% fat, and 50% to 55% carbohydrate, on average, in order to provide WL. In general, the meal plans included 3 main meals (breakfast, lunch, and dinner) and three snacks (mid-morning, mid-afternoon, and bedtime), and low saturation and trans fats, cholesterol, salt (sodium), and added sugars. All diets were designed according to Dietary Guidelines for Americans, 2010 (21). Low-calorie diets produced an energy deficit of 500 to 750 and 1000 to 1500 kcal per day for slow and rapid WL, respectively. At the end of the study, anthropometric and biochemical assessments were conducted on the individuals (18 individuals in rapid WL and 18 individuals in slow WL), who reached the desired WL. All subjects provided their written informed consent, and the study protocol was approved by the ethics committee of Jundishapur University of Medical Sciences (Act No. IR.AJUMS.REC.1394.212).
Most women will need to eat and drink fewer calories and get the right amount of healthy foods to lose weight. Increasing exercise or physical activity may help with weight loss, but choosing healthy foods (lean protein, whole grains, vegetables, and fruits) is what works best for many people to achieve a healthy weight.1 Combining healthy eating with increased physical activity is best. Talk to your doctor or nurse before starting any weight-loss program. He or she can work with you to find the best way for you to lose weight.