In previous studies, elevated ratio of myostatin-to-follistatin, as an indicator of skeletal muscle catabolism, was reported to be greater in rapid WL compared to slow WL (25). The results were consistent with other studies in this field (26). In a study by Martin et al., the impact of these 2 protocols had been compared on the indices of anthropometric and lipid profiles. Their study was conducted in the form of a pilot study on obese postmenopausal females. The results of their study showed that slow WL caused more fat mass reduction and less FFM loss. However, in their study, no differences in lipid profile were observed between slow WL and rapid WL (18).
Blood samples (5 mL) were collected at the beginning and at end of the study during the 12-hour fasting condition. The samples were centrifuged at a low level and serum was separated. Biochemical measurements were performed immediately after sampling. Fasting blood sugar (FBS), high-density lipoprotein (HDL), very low-density lipoprotein (VLDL), triglycerides (TG), and TC were measured by an auto-analyzer (Hitachi, USA). The Friedewald formula was used to calculate LDL levels. Fasting serum insulin concentration was measured by enzyme linked immunosorbent assay (ELISA) kits (Mercodia). The homeostatic model assessment (HOMA) was calculated with the formula: HOMA-IR = [FBS (mg/dL)*FINS (μU/mL)] / 405. (23). Quantitative insulin sensitivity check index (QUICKI) was calculated on the basis of suggested formulas: 1 / [log (Insulin μU/mL) + log (Glucose mg/dL)]. (24). The HOMA-B (pancreatic beta cell function) was computed as follow: 20 × FINS (μIU/mL)/fasting glucose (mmol/mL)-3.5. Insulin sensitivity was derived using the formula: HOMA-S (insulin sensitivity) = 22.5/(insulin (mU/L) × glucose (mmol/L)). All biochemical assays were performed in duplicates and the mean was calculated for each subject.
If you are on the birth control pill, it depends on which one. Some pills are just progesterone. if that’s the case then your insulin sensitivity may be a BIT hampered. If you have a progesterone/estrogen combination pill then its a bit less easy to tell how you may be experiencing hormone fluctuations and which is more dominant in you. If they are well balanced then I wouldn’t worry too much about taking care of them and would consider cycling the ‘normal’ way
Fitness and nutrition were my two focus areas, and I completed some sort of action for them each day. Fitness each day looked different, but it was usually an hour of busting my butt. If you’re a list person, this is a tangible action that can be “checked off your list.” In my opinion, nutrition is not as concrete. Again, if you’re a list person, it’s a little difficult because either you write things like “eat balanced, nutritious breakfast” or “don’t eat sweets” or whatever. It also lasts all day long instead of one hour. This category leaves a lot of room for improvement.
Hi Gary! Thank you for the nice comment, Sorry it took so long for me to reply. I understand about seeing pictures of yourself and it’s wonderful that it motivated you. For a lot of people it doesn’t. It didn’t for me for years. Until one day, I was digging in my drawer and I found a picture of me and I couldn’t believe my eyes! My family said it wasn’t me, well it was me! I recognize my shoes and handbag anywhere! I keep that picture on my fridge, and when the urge to eat hits, I look at it, breath and ask myself,am I really hungry?
If you don’t have an established exercise routine, simply walking is the best first step toward weight loss. “Walking is a pretty good entry point for people,” says Gagliardi. This is particularly true if you have been out of the gym for a while and want to ease back into a workout routine. One small study published in The Journal of Exercise Nutrition & Biochemistry found that obese women who did a walking program for 50 to 70 minutes three days per week for 12 weeks significantly slashed their visceral fat compared to a sedentary control group.
It can be harder to lose weight after menopause. In fact, many women gain an average of 5 pounds after menopause.5 Lower estrogen levels may play a role in weight gain after menopause. But weight gain may be caused by your metabolism slowing down as you age, less-healthful eating habits, and being less active. You also lose muscle mass as you age, so you use fewer calories.